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NOVO - Novel approaches for prevention and degeneration of pathogenic bacteria biofilms formed on medical devices e.g. catheters.

Project Budget: 2,971,045

Coordinator: Prof. Georg Guebitz, BOKU

Biofilms are bacterial communities encased in a self-produced hydrated polymeric matrix. An important characteristic of microbial biofilms is their innate resistance to the immune system and to antibiotics. This resistance has made microbial biofilms a common cause of medical infections, and of difficult-to-treat infections caused by colonized foreign bodies. Prevention of biofilm formation is a necessary step in the successful prophylaxis of such infections. More than 60% of bacterial infections currently treated in hospitals are caused by bacterial biofilms. Biofilms are a major cause of infections associated with medical indwelling implants such as catheters. The number of implant-associated infections approaches 1 million/year in the US alone, and their direct medical costs exceed $3 billion annually. Catheter-associated biofilm urinary tract infections (UTI) alone account for approximately 40% of all hospital-acquired infections

Beneficiary name

Country

University of Natural Resources and Life Sciences, Vienna

AT

Bar-Ilan University

IL

Universitat Politècnica de Catalunya

ES

University of Duisburg-Essen

DE

Emergency Medicine Institute "Pirogov"

BG

Synovo GmbH

DE

TECMINHO

PT

Qualizyme  Biotechnology

AT

PRONEFRO,S.A.

PT

Degania Silicon Ltd.

IL

OSM-DAN Ltd.

IL

http://www.fp7-novo.eu/